When I was an SHO many years ago, we had a case of PUO. Pyrexia of unknown origin. Young man, admitted with chills and rigors. History unrevealing. Denies IV drug use recent travel etc. Blood cultures grew all sorts of unusual organisms, not normally seen in septicaemia, and not normally seen in immunosuppressed either. Echo didn’t show any endocarditis.
The blood culture was positive for Corynebacteria one day and for Strep pyogenes a few days later and then for Enterococcus faecalis a few days later. The medical team were getting increasingly perplexed as to what is going on. The whole body CT scan was unremarkable. We are starting to suspect self induced disease. There was however some microscopic haematuria. The fevers were genuine, and the blood cultures were carefully taken and processed by medical staff, so there is no chance he can contaminate the samples.
Eventually, after much interrogation, he revealed that he and his wife has quite unusual sexual practices. He would insert a knitting needle into the urethra of his erect penis prior intercourse. Somehow that introduced all sorts of organisms into his blood stream. What really surprised me was the different bugs were cultured during his stay in the hospital. How could he and his wife quite manage his deviant sexual behaviours inside the ward? Perhaps the fact he was put in an isolation ward under infectious disease gave them an opportunity.